ZW10

Across TCGA patient cohorts, ZW10 protein abundance is significantly associated with the RNA expression of many other genes, with 10,182 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZW10-associated genes across cancer lineages are DLAT, ABCA8, and F13A1. Each is linked with ZW10 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZW10-to-partner and partner-to-ZW10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZW10 versus DLAT in OV, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZW10→partner) and Y-score (partner→ZW10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DLAT →	+0.601	+0.205	<.001	.001	3	6
UCEC	ABCA8 →	-1.214	-0.124	<.001	.003	3	6
COAD	F13A1 →	-1.349	-0.133	<.001	.003	3	5
UCEC	RHOJ →	-0.892	-0.182	<.001	<.001	3	5
UCEC	ABI3BP →	-1.041	-0.137	<.001	.001	3	5
HNSC	CASQ2 →	-1.762	-0.136	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,182 associations by consensus.

ZW10 vs DLAT — OV

Explore this scatter interactively →