ZSWIM2

Across TCGA cell cohorts, ZSWIM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 261 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ZSWIM2-associated GO terms across cancer lineages are Response to hydrostatic pressure, Protein-containing complex disassembly, and Biological process involved in symbiotic interaction. Each is linked with ZSWIM2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZSWIM2-to-partner and partner-to-ZSWIM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to hydrostatic pressure grouped by ZSWIM2-low versus ZSWIM2-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSWIM2→partner) and Y-score (partner→ZSWIM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Response to hydrostatic pressure →	+0.137	+0.144	<.001	.005	3	5
LUNG_NSCLC_LUSC	Protein-containing complex disassembly →	+0.073	+0.040	<.001	.008	2	6
CNS	Biological process involved in symbiotic interaction →	+0.054	+0.096	<.001	.002	3	4
BLOOD_Leukemia	Protein folding →	+0.045	+0.020	<.001	.003	3	4
CNS	Membrane disassembly →	+0.062	+0.040	.002	.007	2	4
CNS	Endosomal lumen acidification →	+0.068	+0.122	.007	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 261 associations by consensus.

Response to hydrostatic pressure by ZSWIM2 expression — CNS

Explore this box plot interactively →