ZP2

Across TCGA patient cohorts, ZP2 protein abundance is significantly associated with the RNA expression of many other genes, with 70 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ZP2-associated genes across cancer lineages are MOCS3, CYP2C9, and C5orf34. Each is linked with ZP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZP2-to-partner and partner-to-ZP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZP2 versus MOCS3 in HNSC, with a Pearson correlation of -0.89.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZP2→partner) and Y-score (partner→ZP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MOCS3 →	-0.733	-0.826	<.001	.003	3	1
HNSC	CYP2C9 →	-1.083	-0.703	<.001	.002	3	1
HNSC	C5orf34 →	-0.767	-0.595	.002	.004	3	1
HNSC	ADIPOQ →	-1.000	-0.596	.001	.004	3	1
HNSC	GUSBP1 →	-1.182	-0.596	.004	.004	3	1
HNSC	FAM163B →	-0.363	-0.803	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 70 associations by consensus.

ZP2 vs MOCS3 — HNSC

Explore this scatter interactively →