ZP2

Across TCGA cell cohorts, ZP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 290 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ZP2-associated GO terms across cancer lineages are Menaquinone catabolic process, Purkinje myocyte action potential, and Membrane depolarization during Purkinje myocyte cell action potential. Each is linked with ZP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZP2-to-partner and partner-to-ZP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Menaquinone catabolic process grouped by ZP2-low versus ZP2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZP2→partner) and Y-score (partner→ZP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Menaquinone catabolic process →	+1.433	+0.008	<.001	.008	3	3
OVARY	Purkinje myocyte action potential →	+0.915	+0.008	.001	.008	2	3
OVARY	Membrane depolarization during Purkinje myocyte cell action potential →	+0.915	+0.008	.001	.008	2	3
BREAST	Macrophage derived foam cell differentiation →	-0.837	-0.494	<.001	.007	3	2
BREAST	Spliceosome-depend formation of circular RNA →	-0.184	-0.502	<.001	.007	3	2
BREAST	Regulation of odontoblast differentiation →	-0.133	-0.367	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 290 associations by consensus.

Menaquinone catabolic process by ZP2 expression — OVARY

Explore this box plot interactively →