ZNRF2

Across TCGA patient cohorts, ZNRF2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,358 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZNRF2-associated proteins across cancer lineages are ZNRF2_S135, GGCT, and DBNL. Each is linked with ZNRF2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNRF2-to-partner and partner-to-ZNRF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNRF2 versus ZNRF2_S135 in BRCA, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNRF2→partner) and Y-score (partner→ZNRF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZNRF2_S135 →	+0.744	+0.679	.001	.001	3	5
BRCA	GGCT →	+0.610	+0.985	<.001	<.001	3	5
BRCA	DBNL →	+0.231	+0.919	<.001	<.001	3	4
BRCA	COASY →	+0.295	+0.514	<.001	<.001	3	3
BRCA	DDAH1 →	+0.678	+0.779	<.001	<.001	3	3
LSCC	DHX8 →	+0.301	+0.395	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,358 associations by consensus.

ZNRF2 vs ZNRF2_S135 — BRCA

Explore this scatter interactively →