Across TCGA cell cohorts, ZNF891 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF891-associated genes across cancer lineages are UTF1, REG1B, and TFDP3. Each is linked with ZNF891 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF891-to-partner and partner-to-ZNF891 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF891→partner) and Y-score (partner→ZNF891) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	UTF1 →	+0.018	+3.632	<.001	.003	3	1
LARGE_INTESTINE	REG1B →	+2.981	+3.196	<.001	.007	3	1
LARGE_INTESTINE	TFDP3 →	+0.020	+3.196	.001	.007	3	1
LARGE_INTESTINE	C14orf180 →	+0.104	+4.155	.002	.003	3	1
LARGE_INTESTINE	NEXMIF →	+0.285	+4.518	<.001	<.001	3	1
LARGE_INTESTINE	GSC2 →	+0.116	+3.688	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

ZNF891 survival (RNA) · tumor vs normal (RNA) · all ZNF891 data types