ZNF879

Across TCGA patient cohorts, ZNF879 mutation is significantly associated with the total protein of many other genes, with 47 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF879-associated genes across cancer lineages are ASNS, STAT3_pY705, and ATM. Each is linked with ZNF879 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF879-to-partner and partner-to-ZNF879 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by ZNF879-low versus ZNF879-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF879→partner) and Y-score (partner→ZNF879) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ASNS →	+0.655	+3.008	.001	.019	3	2
UCEC	STAT3_pY705 →	-0.243	-1.289	.003	.023	3	2
UCEC	ATM →	-0.473	-2.687	.001	.005	3	2
UCEC	4E-BP1 →	+0.353	+2.058	<.001	<.001	3	2
COAD	ARID1A →	+0.222	+2.825	.011	.033	3	1
UCEC	14-3-3_beta →	-0.104	-3.880	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

ASNS by ZNF879 expression — COAD

Explore this box plot interactively →