ZNF879

Across TCGA cell cohorts, ZNF879 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,859 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZNF879-associated GO terms across cancer lineages are Granzyme-mediated apoptotic signaling pathway, Post-transcriptional gene silencing, and Regulation of monoatomic cation transmembrane transport. Each is linked with ZNF879 in more than 8 cancer types. Because this analysis shows association rather than direction, both ZNF879-to-partner and partner-to-ZNF879 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Granzyme-mediated apoptotic signaling pathway grouped by ZNF879-low versus ZNF879-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF879→partner) and Y-score (partner→ZNF879) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Granzyme-mediated apoptotic signaling pathway →	+0.107	+0.798	<.001	<.001	3	9
BONE	Post-transcriptional gene silencing →	+0.065	+0.482	.001	.003	3	9
BREAST	Regulation of monoatomic cation transmembrane transport →	-0.062	-0.899	.001	.006	3	8
SOFT_TISSUE	Negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains →	-0.078	-0.727	<.001	<.001	3	8
SOFT_TISSUE	RNA splicing, via transesterification reactions →	+0.060	+0.706	.003	.001	3	8
SOFT_TISSUE	Hormone metabolic process →	-0.073	-0.533	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,859 associations by consensus.

Granzyme-mediated apoptotic signaling pathway by ZNF879 expression — SOFT_TISSUE

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