ZNF835

Across TCGA cell cohorts, ZNF835 mutation is significantly associated with the RNA expression of many other genes, with 1,360 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF835-associated genes across cancer lineages are NANOS2, GKAP1, and IQCF1. Each is linked with ZNF835 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF835-to-partner and partner-to-ZNF835 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NANOS2 grouped by ZNF835-low versus ZNF835-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF835→partner) and Y-score (partner→ZNF835) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	NANOS2 →	+0.015	+3.491	<.001	.008	3	3
LARGE_INTESTINE	GKAP1 →	+0.764	+2.743	<.001	.001	3	3
OESOPHAGUS	IQCF1 →	+0.071	+3.906	<.001	.007	2	3
OESOPHAGUS	GSG1L2 →	+0.026	+3.392	<.001	.007	3	2
URINARY_TRACT	C14orf180 →	+0.292	+4.087	.002	.009	3	2
LARGE_INTESTINE	TNRC6B →	+0.769	+2.386	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,360 associations by consensus.

NANOS2 by ZNF835 expression — PANCREAS

Explore this box plot interactively →