ZNF831

Across TCGA patient cohorts, ZNF831 mutation is significantly associated with the RNA expression of many other genes, with 7,152 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF831-associated genes across cancer lineages are PARP2, GEMIN2, and PSMC1. Each is linked with ZNF831 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF831-to-partner and partner-to-ZNF831 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PARP2 grouped by ZNF831-low versus ZNF831-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF831→partner) and Y-score (partner→ZNF831) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PARP2 →	+0.426	+2.078	<.001	<.001	3	6
LUSC	GEMIN2 →	+0.318	+1.768	.002	.001	3	6
STAD	PSMC1 →	+0.409	+3.219	<.001	<.001	3	5
STAD	RAD51AP1 →	+0.602	+2.597	.003	.005	3	5
STAD	RCC1 →	+0.552	+3.354	.004	.004	3	5
LUAD	FMO4 →	-0.401	-2.275	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,152 associations by consensus.

PARP2 by ZNF831 expression — UCEC

Explore this box plot interactively →