ZNF804B

Across TCGA patient cohorts, ZNF804B mutation is significantly associated with the RNA expression of many other genes, with 6,287 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF804B-associated genes across cancer lineages are GLOD4, DEPDC1, and TRAIP. Each is linked with ZNF804B in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF804B-to-partner and partner-to-ZNF804B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GLOD4 grouped by ZNF804B-low versus ZNF804B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF804B→partner) and Y-score (partner→ZNF804B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GLOD4 →	+0.396	+1.721	<.001	<.001	3	6
COAD	DEPDC1 →	+0.662	+1.947	<.001	.009	3	6
LUAD	TRAIP →	+0.400	+2.514	<.001	<.001	3	5
READ	AUNIP →	+0.636	+3.188	.009	.009	3	5
READ	NUSAP1 →	+0.759	+3.188	.003	.009	2	6
READ	RFC4 →	+0.660	+3.188	<.001	.009	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,287 associations by consensus.

GLOD4 by ZNF804B expression — UCEC

Explore this box plot interactively →