ZNF780B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF780B protein abundance is significantly associated with the RNA expression of many other genes, with 196 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF780B-associated genes across cancer lineages are CPQ, SFRP1, and LYL1. Each is linked with ZNF780B in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF780B-to-partner and partner-to-ZNF780B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF780B versus CPQ in GBM, with a Pearson correlation of 0.84.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF780B→partner) and Y-score (partner→ZNF780B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMCPQ →+0.630+0.712.001.00631
GBMSFRP1 →+2.219+0.969.002.00631
GBMLYL1 →+1.491+0.774.005.00531
GBMPALD1 →+1.348+0.712<.001.00631
GBMNDUFS7 →+0.538+0.712.005.00631
GBMKCNJ5 →+1.213+0.712.003.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 196 associations by consensus.

ZNF780B vs CPQ — GBM

Per-sample scatter of ZNF780B vs CPQ in GBM (Pearson r = 0.84).

Explore this scatter interactively →

Exploration