ZNF77

Across TCGA patient cohorts, ZNF77 mutation is significantly associated with the RNA expression of many other genes, with 4,097 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF77-associated genes across cancer lineages are MAGEB10, ERHP2, and MIR4726. Each is linked with ZNF77 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF77-to-partner and partner-to-ZNF77 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB10 grouped by ZNF77-low versus ZNF77-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF77→partner) and Y-score (partner→ZNF77) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MAGEB10 →	+0.134	+4.653	<.001	.004	3	3
SKCM	ERHP2 →	+0.048	+4.411	<.001	.005	3	3
BRCA	MIR4726 →	+0.449	+5.382	<.001	.003	3	2
BRCA	MIR5787 →	+0.385	+5.215	<.001	.003	3	2
PRAD	BNIP3P41 →	+0.039	+7.939	<.001	.008	3	2
PRAD	IGLVVI-22-1 →	+0.179	+7.939	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,097 associations by consensus.

MAGEB10 by ZNF77 expression — CESC

Explore this box plot interactively →