ZNF77

Across TCGA pan-cancer cohorts, ZNF77 RNA is linked to patient survival in 30 of 34 cancer types, making it the most broadly survival-associated ZNF77 data layer compared with 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher ZNF77 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ZNF77 expression acts as an unfavorable survival marker, although some lineages such as LUAD and UCEC show a favorable association.

LUAD, KICH, and UCEC are the cancer types where ZNF77 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.734	0.601	<.001	107	view →
KICH	DFS	Median	III,IV	0.308	0.942	.001	72	view →
UCEC	DFS	Tertile	III,IV	0.700	0.402	.001	66	view →
ACC	DFS	Median	All	0.414	0.738	<.001	62	view →
STAD	DFS	Tertile	IV	0.111	0.862	.002	39	view →
PRAD	DFS	Quartile	All	0.687	0.868	.009	28	view →
UVM	DFS	Quartile	III,IV	0.099	1.000	.006	26	view →
KIRC	DFS	Tertile	All	0.716	0.588	.009	24	view →
PAAD	OS	Tertile	All	0.480	0.223	.008	20	view →
LUSC	OS	Median	All	0.817	0.730	.005	18	view →
LGG	DFS	Tertile	All	0.787	0.887	.003	16	view →
BLCA	DFS	Median	All	0.401	0.279	.020	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 30 lineages.

ZNF77–LUAD (DFS)

Open the LUAD breakdown →