ZNF77

Across TCGA cell cohorts, ZNF77 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,572 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ZNF77-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, Epigenetic regulation of gene expression, and Heterochromatin organization. Each is linked with ZNF77 in more than 13 cancer types. Because this analysis shows association rather than direction, both ZNF77-to-partner and partner-to-ZNF77 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by ZNF77-low versus ZNF77-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF77→partner) and Y-score (partner→ZNF77) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of gene expression, epigenetic →	+0.053	+0.744	<.001	<.001	3	14
BONE	Epigenetic regulation of gene expression →	+0.083	+0.758	.001	.001	2	14
LARGE_INTESTINE	Heterochromatin organization →	+0.036	+0.456	<.001	<.001	3	13
LARGE_INTESTINE	Heterochromatin formation →	+0.038	+0.448	<.001	<.001	3	13
BONE	Renal system process →	-0.116	-0.707	<.001	<.001	3	12
PANCREAS	Subtelomeric heterochromatin formation →	+0.083	+0.527	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,572 associations by consensus.

Negative regulation of gene expression, epigenetic by ZNF77 expression — SOFT_TISSUE

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