ZNF77

Across TCGA cell cohorts, ZNF77 mutation is significantly associated with the RNA expression of many other genes, with 266 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF77-associated genes across cancer lineages are AVP, TRPA1, and ZNF330. Each is linked with ZNF77 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF77-to-partner and partner-to-ZNF77 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by ZNF77-low versus ZNF77-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF77→partner) and Y-score (partner→ZNF77) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	AVP →	+0.037	+3.047	<.001	.001	3	1
LARGE_INTESTINE	TRPA1 →	+0.537	+3.559	<.001	.001	3	1
LARGE_INTESTINE	ZNF330 →	+0.511	+3.067	.005	.009	3	1
LARGE_INTESTINE	NPRL2 →	+0.459	+3.212	.007	.006	3	1
LARGE_INTESTINE	DPH5 →	+0.551	+3.212	.006	.006	3	1
LARGE_INTESTINE	FGF23 →	+0.324	+3.584	.008	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 266 associations by consensus.

AVP by ZNF77 expression — LARGE_INTESTINE

Explore this box plot interactively →