ZNF713

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF713 mutation is significantly associated with the RNA expression of many other genes, with 2,799 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF713-associated genes across cancer lineages are SPCS2P4, NRBF2, and ATP6V1E1P3. Each is linked with ZNF713 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF713-to-partner and partner-to-ZNF713 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPCS2P4 grouped by ZNF713-low versus ZNF713-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF713→partner) and Y-score (partner→ZNF713) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSPCS2P4 →+0.641+2.624<.001.00533
UCECNRBF2 →+0.422+3.839.008<.00133
SKCMATP6V1E1P3 →+0.239+3.481<.001.00332
UCECCCDC163 →+0.596+3.716<.001<.00132
UCECINCENP →+0.676+3.708.002<.00132
UCECNOCT →+0.837+3.818<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,799 associations by consensus.

SPCS2P4 by ZNF713 expression — UCEC

Box plot of SPCS2P4 in ZNF713-low vs ZNF713-high samples in UCEC.

Explore this box plot interactively →

Exploration