ZNF713

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, ZNF713 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of ZNF713’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where ZNF713 RNA is repressed in tumor relative to normal tissue. In most cancer types ZNF713 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, THCA, and HNSC are the cancer types where ZNF713 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF713 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KICHAllAll−0.710<.00110view →
THCAAllII,III,IV−0.461<.0019view →
HNSCAllAll+0.409<.0019view →
LIHCFemaleII,III,IV+0.389<.0018view →
CHOLMaleAll+1.236<.0015view →
BLCAAllAll+0.511.0145view →
STADAllII,III,IV+0.549<.0014view →
BRCAAllII,III,IV+0.392<.0014view →
KIRPAllIV+0.679.0302view →
COADAllAll+0.198.0122view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

ZNF713–KICH

Tumor-vs-normal expression box plot for ZNF713 RNA in KICH.

Open the KICH breakdown →

Exploration