ZNF713

Across TCGA patient cohorts, ZNF713 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF713-associated genes across cancer lineages are EGFR_pY1068, eIF4G, and ACC1. Each is linked with ZNF713 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF713-to-partner and partner-to-ZNF713 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by ZNF713-low versus ZNF713-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF713→partner) and Y-score (partner→ZNF713) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.270	-1.807	.009	.027	3	1
UCEC	eIF4G →	+0.291	+2.999	.023	.035	3	1
UCEC	ACC1 →	+0.317	+3.013	.034	.018	3	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.576	+2.321	.006	.006	3	1
UCEC	mTOR_pS2448 →	-0.149	-2.095	.015	.017	3	1
UCEC	p62 Lck ligand →	+0.365	+3.469	.006	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

EGFR_pY1068 by ZNF713 expression — UCEC

Explore this box plot interactively →