ZNF708

Across TCGA patient cohorts, ZNF708 mutation is significantly associated with the RNA expression of many other genes, with 3,630 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF708-associated genes across cancer lineages are RNA5SP325, ATP6V1E1P2, and LINC02502. Each is linked with ZNF708 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF708-to-partner and partner-to-ZNF708 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP325 grouped by ZNF708-low versus ZNF708-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF708→partner) and Y-score (partner→ZNF708) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNA5SP325 →	+0.245	+3.623	<.001	.001	3	3
BLCA	ATP6V1E1P2 →	+0.145	+5.588	.009	.004	3	3
SKCM	LINC02502 →	+0.662	+3.922	<.001	.002	3	3
HNSC	RNA5SP389 →	+0.206	+5.351	<.001	.002	3	2
HNSC	RNU6-628P →	+0.490	+4.084	.001	.005	3	2
UCEC	RNA5SP411 →	+0.882	+1.531	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,630 associations by consensus.

RNA5SP325 by ZNF708 expression — SKCM

Explore this box plot interactively →