ZNF701

Across TCGA patient cohorts, ZNF701 mutation is significantly associated with the RNA expression of many other genes, with 1,898 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF701-associated genes across cancer lineages are RNU7-87P, SUGT1P4, and INTS4. Each is linked with ZNF701 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF701-to-partner and partner-to-ZNF701 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-87P grouped by ZNF701-low versus ZNF701-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF701→partner) and Y-score (partner→ZNF701) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU7-87P →	+0.282	+8.057	<.001	.005	3	3
SKCM	SUGT1P4 →	+0.165	+3.743	<.001	.002	3	2
UCEC	INTS4 →	+0.309	+3.711	.002	<.001	3	2
UCEC	MTA2 →	+0.367	+2.743	.001	.002	3	2
UCEC	TMEM138 →	+0.215	+2.212	.007	<.001	3	2
SKCM	NTAN1 →	+0.462	+3.238	.004	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,898 associations by consensus.

RNU7-87P by ZNF701 expression — BRCA

Explore this box plot interactively →