Across TCGA cell cohorts, ZNF700 mutation is significantly associated with the RNA expression of many other genes, with 266 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF700-associated genes across cancer lineages are C14orf180, SCYGR5, and IL3. Each is linked with ZNF700 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF700-to-partner and partner-to-ZNF700 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF700→partner) and Y-score (partner→ZNF700) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	C14orf180 →	+0.156	+3.594	<.001	.005	3	2
BONE	SCYGR5 →	+0.220	+5.169	<.001	.004	3	1
LUNG_SCLC	IL3 →	+0.055	+5.029	<.001	.006	3	1
LUNG_SCLC	PRAMEF10 →	+1.180	+5.643	<.001	.002	3	1
LUNG_SCLC	PRAMEF17 →	+0.013	+5.643	<.001	.002	3	1
LUNG_SCLC	SPINK8 →	+0.513	+5.029	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 266 associations by consensus.

Exploration

ZNF700 survival (RNA) · tumor vs normal (RNA) · all ZNF700 data types