ZNF700

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ZNF700 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated ZNF700 data layer compared with 9 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ZNF700 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ZNF700 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BLCA show a favorable association.

HNSC, ACC, and KIRC are the cancer types where ZNF700 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSMedianAll0.8060.693<.001139view →
ACCDFSTertileAll0.3630.773<.00198view →
KIRCDFSTertileII,III,IV0.3630.664<.00179view →
KICHDFSTertileIII,IV0.2570.931.00273view →
BLCADFSMedianAll0.5580.461.00455view →
LGGDFSMedianAll0.6720.806<.00151view →
SKCMOSMedianIV1.0000.278.00634view →
UVMDFSQuartileIII,IV0.1830.832<.00126view →
BRCAOSQuartileAll0.9730.949.02324view →
MESODFSMedianIV0.1890.521.00224view →
LAMLDFSQuartileAll0.5570.268.00818view →
PRADOSTertileAll0.7500.940.00316view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

Exploration