Across TCGA cell cohorts, ZNF69 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF69-associated genes across cancer lineages are OR4C12, GYPB, and H4C6. Each is linked with ZNF69 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF69-to-partner and partner-to-ZNF69 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF69→partner) and Y-score (partner→ZNF69) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR4C12 →	+0.017	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	GYPB →	+0.074	+4.544	.007	.003	3	1
LUNG_NSCLC_LUAD	H4C6 →	+0.205	+4.212	.005	.007	3	1
LUNG_NSCLC_LUAD	SPO11 →	+0.057	+4.947	<.001	.001	3	1
BLOOD_Leukemia	OR11H1 →	+0.045	+5.201	.002	.006	3	1
SKIN	SPACA5 →	+0.110	+4.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

ZNF69 survival (RNA) · tumor vs normal (RNA) · all ZNF69 data types