Across TCGA cell cohorts, ZNF679 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ZNF679-associated genes across cancer lineages are CD300H, GH1, and FAM47C. Each is linked with ZNF679 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF679-to-partner and partner-to-ZNF679 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF679→partner) and Y-score (partner→ZNF679) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	CD300H →	+0.137	+4.169	<.001	.001	3	2
OESOPHAGUS	GH1 →	+0.049	+4.906	<.001	.006	3	1
SKIN	FAM47C →	+0.003	+2.977	<.001	.006	3	1
LUNG_NSCLC_LUAD	PRAMEF2 →	+0.008	+3.734	.001	.006	3	1
LUNG_NSCLC_LUAD	DTHD1 →	+0.109	+4.273	.003	.006	3	1
LUNG_NSCLC_LUAD	OR8B8 →	+0.019	+3.734	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

ZNF679 survival (RNA) · tumor vs normal (RNA) · all ZNF679 data types