Across TCGA pan-cancer cohorts, ZNF679 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of ZNF679’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ZNF679 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ZNF679 is over-expressed in tumor.

HNSC, KIRP, and LUSC are the cancer types where ZNF679 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF679 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.026	.017	3	view →
KIRP	Female	All	+0.077	.042	1	view →
LUSC	Male	All	+0.019	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: ZNF679 RNA expression & survival · all ZNF679 data types