ZNF667-AS1

Across TCGA patient cohorts, ZNF667-AS1 mutation is significantly associated with the RNA expression of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF667-AS1-associated genes across cancer lineages are HNRNPCL3, RN7SL140P, and MIA-RAB4B. Each is linked with ZNF667-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF667-AS1-to-partner and partner-to-ZNF667-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HNRNPCL3 grouped by ZNF667-AS1-low versus ZNF667-AS1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF667-AS1→partner) and Y-score (partner→ZNF667-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HNRNPCL3 →	+0.071	+2.871	<.001	.007	3	1
UCEC	RN7SL140P →	+0.165	+4.582	<.001	<.001	3	1
UCEC	MIA-RAB4B →	+0.128	+2.863	<.001	.004	3	1
UCEC	MICOS10-NBL1 →	+0.142	+2.957	<.001	.007	3	1
UCEC	AQP7P3 →	+0.063	+4.582	<.001	<.001	3	1
UCEC	RPL32P36 →	+0.164	+2.863	.003	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

HNRNPCL3 by ZNF667-AS1 expression — UCEC

Explore this box plot interactively →