ZNF667-AS1

Across TCGA pan-cancer cohorts, ZNF667-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ZNF667-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher ZNF667-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ZNF667-AS1 expression acts as an unfavorable survival marker, although some lineages such as UVM and CESC show a favorable association.

UVM, SKCM, and CESC are the cancer types where ZNF667-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Median	All	0.899	0.333	<.001	131	view →
SKCM	OS	Tertile	All	0.231	0.394	<.001	51	view →
CESC	OS	Quartile	All	0.894	0.704	.002	42	view →
PAAD	OS	Tertile	All	0.549	0.286	.001	37	view →
LUAD	DFS	Tertile	All	0.861	0.674	.002	37	view →
KIRC	DFS	Median	All	0.723	0.519	.002	29	view →
PCPG	DFS	Tertile	All	0.922	0.772	.030	22	view →
HNSC	DFS	Quartile	III,IV	0.494	0.218	.010	20	view →
LGG	DFS	Tertile	All	0.649	0.848	.002	20	view →
KIRP	DFS	Median	III,IV	0.616	0.138	.004	18	view →
ACC	DFS	Median	All	0.396	0.702	.024	12	view →
LUSC	DFS	Quartile	III,IV	0.210	0.563	.005	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ZNF667-AS1–UVM (OS)

Open the UVM breakdown →