ZNF667-AS1

Across TCGA pan-cancer cohorts, ZNF667-AS1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of ZNF667-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ZNF667-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ZNF667-AS1 is over-expressed in tumor, although a few such as KIRC and BLCA show the opposite, repressed pattern.

KIRC, BLCA, and COAD are the cancer types where ZNF667-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF667-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	−1.602	<.001	11	view →
BLCA	All	All	−1.284	.001	10	view →
COAD	Male	II,III,IV	−1.060	<.001	9	view →
HNSC	Male	II,III,IV	−0.894	<.001	9	view →
THCA	Male	III,IV	−0.778	<.001	9	view →
KIRP	All	All	−1.767	<.001	7	view →
STAD	Female	All	−1.715	<.001	7	view →
KICH	Male	All	−1.593	<.001	7	view →
BRCA	All	All	−0.888	<.001	6	view →
LUAD	Female	All	−0.693	.001	3	view →
READ	Female	All	−2.031	.002	2	view →
LUAD	All	IV	+1.650	.026	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

ZNF667-AS1–KIRC

Open the KIRC breakdown →