ZNF664

Across TCGA patient cohorts, ZNF664 mutation is significantly associated with the RNA expression of many other genes, with 1,280 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF664-associated genes across cancer lineages are RNU6-391P, MIR4472-1, and USP9YP8. Each is linked with ZNF664 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF664-to-partner and partner-to-ZNF664 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-391P grouped by ZNF664-low versus ZNF664-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF664→partner) and Y-score (partner→ZNF664) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-391P →	+0.202	+7.930	<.001	.008	3	3
HNSC	MIR4472-1 →	+0.814	+5.182	<.001	.007	3	3
LUSC	USP9YP8 →	+0.399	+5.906	<.001	.001	3	3
ACC	GTF2F2P2 →	+0.258	+5.813	<.001	<.001	3	2
COAD	RN7SL98P →	+0.256	+3.108	<.001	.007	3	2
COAD	RN7SL632P →	+0.431	+3.205	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,280 associations by consensus.

RNU6-391P by ZNF664 expression — LUAD

Explore this box plot interactively →