Across TCGA patient cohorts, ZNF630 mutation is significantly associated with the RNA expression of many other genes, with 3,987 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF630-associated genes across cancer lineages are IGHD3-16, ATF4P1, and RNU6-470P. Each is linked with ZNF630 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF630-to-partner and partner-to-ZNF630 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF630→partner) and Y-score (partner→ZNF630) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGHD3-16 →	+0.678	+1.572	.001	<.001	3	3
UCEC	ATF4P1 →	+0.033	+1.980	<.001	<.001	3	3
CESC	RNU6-470P →	+0.506	+3.944	.003	.007	3	2
CESC	MIR7845 →	+0.548	+3.944	.002	.007	3	2
SKCM	FRG1HP →	+0.694	+3.465	.005	.003	3	2
HNSC	VN1R5 →	+0.127	+3.084	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,987 associations by consensus.

Exploration

ZNF630 survival (RNA) · tumor vs normal (RNA) · all ZNF630 data types