RNA, U6 small nuclear 470, pseudogeneGenealiases: []
Q-omics provides the consensus-scored RNU6-470P profile across patient tissues and cancer cell-line models. RNU6-470P expression is associated with patient survival in 7 of 34 cancer types, with the highest sampling consensus in ESCA. Among the 18 cancer types available for tumor–normal comparison, RNU6-470P is differentially expressed in 2, with the highest sampling consensus in BRCA. Additionally, RNU6-470P RNA expression shows 6,017 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight ESCA, BRCA, and STAD as cancer lineages where RNU6-470P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU6-470P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU6-470P survival associations across molecular data types. RNU6-470P RNA expression shows survival associations in the most cancer types (7). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU6-470P RNA expression–survival associations across cancer types. High RNU6-470P expression shows unfavorable associations in DLBC, STAD, COAD and THCA, but favorable associations in ESCA and LAML. The ESCA Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .020). Together, the overview and detailed table identify ESCA as the clearest survival context for RNU6-470P RNA expression.
This table summarizes RNU6-470P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for RNU6-470P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU6-470P shows higher tumor expression in BRCA and HNSC. The BRCA box plot shows higher RNU6-470P RNA expression in tumor versus normal tissue (log2 FC = +0.090, t-test p = .029).
This table shows molecular features associated with RNU6-470P in patient tissues and cancer cell lines. In patient samples, RNU6-470P shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
