RNU6-470P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-470P RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated RNU6-470P data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher RNU6-470P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-470P expression acts as an unfavorable survival marker, although some lineages such as ESCA and LAML show a favorable association.

DLBC, ESCA, and LAML are the cancer types where RNU6-470P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
DLBCOSTertileII,III,IV0.1180.802.02536view →
ESCADFSTertileIII,IV0.6910.362.02036view →
LAMLDFSTertileAll1.0000.334.01230view →
STADOSTertileII,III,IV0.4790.735.01918view →
COADOSTertileIII,IV0.2080.791.0089view →
THCAOSTertileIII,IV0.3670.901.0309view →
LGGDFSTertileAll0.4610.827.0463view →
Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

RNU6-470P–DLBC (OS)

Kaplan–Meier survival curve for RNU6-470P RNA-high vs -low samples in DLBC.

Open the DLBC breakdown →

Exploration