ZNF595

Across TCGA patient cohorts, ZNF595 mutation is significantly associated with the RNA expression of many other genes, with 3,522 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF595-associated genes across cancer lineages are RNU1-17P, AKR1B10P2, and RN7SL66P. Each is linked with ZNF595 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF595-to-partner and partner-to-ZNF595 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-17P grouped by ZNF595-low versus ZNF595-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF595→partner) and Y-score (partner→ZNF595) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU1-17P →	+0.398	+5.103	<.001	.008	3	3
LIHC	AKR1B10P2 →	+0.037	+4.758	<.001	.006	3	2
CESC	RN7SL66P →	+0.168	+5.010	<.001	.009	3	2
LUSC	GOLGA8CP →	+0.037	+2.650	<.001	.008	3	2
LUSC	RN7SKP214 →	+0.284	+2.573	<.001	.009	3	2
LUSC	IGHD5-18 →	+0.838	+2.874	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,522 associations by consensus.

RNU1-17P by ZNF595 expression — CESC

Explore this box plot interactively →