ZNF593

Across TCGA patient cohorts, ZNF593 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,165 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible ZNF593-associated GO terms across cancer lineages are [4Fe-4S] cluster assembly, Regulation of focal adhesion disassembly, and Protein retention in Golgi apparatus. Each is linked with ZNF593 in more than 28 cancer types. Because this analysis shows association rather than direction, both ZNF593-to-partner and partner-to-ZNF593 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, [4Fe-4S] cluster assembly grouped by ZNF593-low versus ZNF593-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF593→partner) and Y-score (partner→ZNF593) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	[4Fe-4S] cluster assembly →	+0.088	+1.133	<.001	<.001	3	29
DLBC	Regulation of focal adhesion disassembly →	-0.084	-0.839	<.001	<.001	3	27
DLBC	Protein retention in Golgi apparatus →	-0.074	-0.855	<.001	<.001	3	27
SCLC	Golgi to endosome transport →	-0.120	-0.793	<.001	<.001	3	27
DLBC	Ribosome-associated ubiquitin-dependent protein catabolic process →	-0.092	-1.047	<.001	<.001	3	27
SCLC	Forebrain neuron development →	-0.130	-0.479	.004	.002	2	28

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,165 associations by consensus.

[4Fe-4S] cluster assembly by ZNF593 expression — DLBC

Explore this box plot interactively →