ZNF593

Across TCGA patient cohorts, ZNF593 protein abundance is significantly associated with the RNA expression of many other genes, with 4,389 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF593-associated genes across cancer lineages are NPM1, GTF2IRD2, and PFDN4. Each is linked with ZNF593 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF593-to-partner and partner-to-ZNF593 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF593 versus NPM1 in UCEC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF593→partner) and Y-score (partner→ZNF593) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NPM1 →	+0.829	+0.296	<.001	.002	3	3
UCEC	GTF2IRD2 →	-0.512	-0.276	.001	.003	3	3
UCEC	PFDN4 →	+0.858	+0.277	.001	.002	3	2
UCEC	AHCY →	+0.750	+0.249	.008	.002	3	2
PDAC	CEP192 →	+0.509	+0.381	.001	.001	3	2
UCEC	RIPK2 →	+0.492	+0.212	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,389 associations by consensus.

ZNF593 vs NPM1 — UCEC

Explore this scatter interactively →