ZNF593

Across TCGA cell cohorts, ZNF593 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,937 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF593-associated GO terms across cancer lineages are Pseudouridine synthesis, rRNA modification, and Quinone metabolic process. Each is linked with ZNF593 in more than 10 cancer types. Because this analysis shows association rather than direction, both ZNF593-to-partner and partner-to-ZNF593 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pseudouridine synthesis grouped by ZNF593-low versus ZNF593-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF593→partner) and Y-score (partner→ZNF593) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pseudouridine synthesis →	+0.120	+1.086	<.001	<.001	3	11
BONE	rRNA modification →	+0.116	+0.970	<.001	<.001	3	11
LARGE_INTESTINE	Quinone metabolic process →	+0.065	+0.404	.005	.005	3	10
BONE	rRNA metabolic process →	+0.141	+0.871	<.001	.001	3	10
BONE	rRNA pseudouridine synthesis →	+0.101	+1.027	.003	<.001	3	10
BLOOD_Lymphoma	Ribosome assembly →	+0.087	+0.944	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,937 associations by consensus.

Pseudouridine synthesis by ZNF593 expression — BONE

Explore this box plot interactively →