ZNF582

Across TCGA cell cohorts, ZNF582 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible ZNF582-associated genes across cancer lineages are OR1L3, FAM47C, and USP17L13. Each is linked with ZNF582 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF582-to-partner and partner-to-ZNF582 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1L3 grouped by ZNF582-low versus ZNF582-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF582→partner) and Y-score (partner→ZNF582) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR1L3 →	+0.029	+5.415	<.001	.004	3	1
SKIN	FAM47C →	+0.006	+4.977	<.001	.007	3	1
OVARY	USP17L13 →	+0.013	+5.807	<.001	.001	3	1
OVARY	KRTAP10-5 →	+0.013	+5.807	<.001	.001	3	1
OVARY	USP17L17 →	+0.013	+5.807	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

OR1L3 by ZNF582 expression — SKIN

Explore this box plot interactively →