ZNF581

Across TCGA patient cohorts, ZNF581 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,294 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ZNF581-associated proteins across cancer lineages are HSPBP1, ZNF787, and TRIM28. Each is linked with ZNF581 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF581-to-partner and partner-to-ZNF581 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF581 versus HSPBP1 in OV, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF581→partner) and Y-score (partner→ZNF581) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HSPBP1 →	+0.313	+0.691	.003	.002	3	6
GBM	ZNF787 →	+0.429	+0.423	<.001	<.001	3	6
OV	TRIM28 →	+0.387	+0.800	.007	.001	2	7
OV	ZNF460 →	+0.493	+0.805	.001	.008	3	5
GBM	U2AF2 →	+0.245	+0.344	.001	.003	3	5
LUAD	PDXDC1_S722 →	-0.855	-0.540	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,294 associations by consensus.

ZNF581 vs HSPBP1 — OV

Explore this scatter interactively →