ZNF581

Across TCGA patient cohorts, ZNF581 protein abundance is significantly associated with the RNA expression of many other genes, with 2,279 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF581-associated genes across cancer lineages are SNORD69, ELOB, and NEBL-AS1. Each is linked with ZNF581 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF581-to-partner and partner-to-ZNF581 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF581 versus SNORD69 in CCRCC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF581→partner) and Y-score (partner→ZNF581) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SNORD69 →	+1.043	+0.453	.002	.002	3	3
OV	ELOB →	+1.248	+0.548	.004	.005	3	2
OV	NEBL-AS1 →	-0.482	-0.676	<.001	.001	3	2
OV	CCL16 →	-0.185	-0.668	<.001	.002	3	2
GBM	TOP3B →	+0.201	+0.327	.004	<.001	3	2
LUAD	GSK3A →	+0.396	+0.352	<.001	<.001	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,279 associations by consensus.

ZNF581 vs SNORD69 — CCRCC

Explore this scatter interactively →