ZNF581

Across TCGA cell cohorts, ZNF581 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,961 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF581-associated GO terms across cancer lineages are Transcription-coupled nucleotide-excision repair, snoRNA localization, and Behavioral response to pain. Each is linked with ZNF581 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZNF581-to-partner and partner-to-ZNF581 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription-coupled nucleotide-excision repair grouped by ZNF581-low versus ZNF581-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF581→partner) and Y-score (partner→ZNF581) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Transcription-coupled nucleotide-excision repair →	+0.091	+0.439	.002	.006	3	10
LARGE_INTESTINE	snoRNA localization →	+0.058	+0.695	.002	.003	3	8
BLOOD_Lymphoma	Behavioral response to pain →	-0.149	-0.799	<.001	<.001	3	7
BLOOD_Lymphoma	Immune response to tumor cell →	-0.203	-1.124	<.001	<.001	3	7
URINARY_TRACT	rRNA pseudouridine synthesis →	+0.113	+0.788	<.001	<.001	3	7
OESOPHAGUS	Response to triglyceride →	-0.178	-0.853	.001	.008	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,961 associations by consensus.

Transcription-coupled nucleotide-excision repair by ZNF581 expression — SKIN

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