ZNF559-ZNF177

Across TCGA patient cohorts, ZNF559-ZNF177 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,153 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF559-ZNF177-associated proteins across cancer lineages are WIZ, B3GLCT, and NRF1. Each is linked with ZNF559-ZNF177 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF559-ZNF177-to-partner and partner-to-ZNF559-ZNF177 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF559-ZNF177 versus WIZ in GBM, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF559-ZNF177→partner) and Y-score (partner→ZNF559-ZNF177) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	WIZ →	+0.421	+0.618	<.001	<.001	3	5
GBM	B3GLCT →	+0.329	+0.372	<.001	<.001	3	5
GBM	NRF1 →	+0.364	+0.435	<.001	<.001	3	5
CCRCC	RING1 →	+0.304	+0.454	<.001	<.001	3	5
LSCC	CASP10 →	-0.461	-0.354	<.001	<.001	3	5
CCRCC	ISG20 →	-0.619	-0.342	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,153 associations by consensus.

ZNF559-ZNF177 vs WIZ — GBM

Explore this scatter interactively →