ZNF556

Across TCGA patient cohorts, ZNF556 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,601 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF556-associated proteins across cancer lineages are PIK3C2B, HDGFL2, and KHSRP. Each is linked with ZNF556 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF556-to-partner and partner-to-ZNF556 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF556 versus PIK3C2B in OV, with a Pearson correlation of -0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF556→partner) and Y-score (partner→ZNF556) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PIK3C2B →	-0.579	-0.712	<.001	.002	3	3
OV	HDGFL2 →	+0.398	+0.780	.001	.001	3	3
OV	KHSRP →	+0.264	+0.712	<.001	<.001	3	3
HNSC	ZNF185_S153 →	-1.158	-0.991	.002	<.001	3	2
LSCC	ZNF326 →	+0.301	+0.585	<.001	<.001	3	2
LSCC	ZYX →	-0.271	-0.607	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,601 associations by consensus.

ZNF556 vs PIK3C2B — OV

Explore this scatter interactively →