ZNF556

Across TCGA cell cohorts, ZNF556 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,710 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZNF556-associated GO terms across cancer lineages are Regulation of RNA splicing, RNA localization, and Protein import into nucleus. Each is linked with ZNF556 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF556-to-partner and partner-to-ZNF556 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of RNA splicing grouped by ZNF556-low versus ZNF556-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF556→partner) and Y-score (partner→ZNF556) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of RNA splicing →	+0.081	+1.348	<.001	.005	3	7
OESOPHAGUS	RNA localization →	+0.091	+1.220	<.001	.001	3	6
OESOPHAGUS	Protein import into nucleus →	+0.092	+1.080	<.001	.007	3	6
BLOOD_Lymphoma	Ribosomal large subunit biogenesis →	+0.080	+0.533	<.001	.007	3	6
SKIN	Purine nucleotide biosynthetic process →	+0.045	+0.551	<.001	.007	3	6
SKIN	Purine-containing compound biosynthetic process →	+0.038	+0.522	.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,710 associations by consensus.

Regulation of RNA splicing by ZNF556 expression — SOFT_TISSUE

Explore this box plot interactively →