ZNF556

Across TCGA cell cohorts, ZNF556 mutation is significantly associated with the RNA expression of many other genes, with 167 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF556-associated genes across cancer lineages are FRRS1L, RAB33A, and DYNC2LI1. Each is linked with ZNF556 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF556-to-partner and partner-to-ZNF556 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FRRS1L grouped by ZNF556-low versus ZNF556-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF556→partner) and Y-score (partner→ZNF556) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	FRRS1L →	+0.040	+4.807	<.001	.006	3	1
SKIN	RAB33A →	+1.512	+3.364	.001	.002	3	1
SKIN	DYNC2LI1 →	-0.572	-3.278	.009	.006	3	1
SKIN	ATP2B2 →	+0.159	+2.777	<.001	.006	3	1
SKIN	ISL1 →	+0.635	+3.364	.002	.002	3	1
SKIN	POC1A →	+0.632	+3.364	.006	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 167 associations by consensus.

FRRS1L by ZNF556 expression — BLOOD_Myeloma

Explore this box plot interactively →