ZNF552

Across TCGA cell cohorts, ZNF552 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible ZNF552-associated genes across cancer lineages are TEX47, S100G, and ELOA3DP. Each is linked with ZNF552 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF552-to-partner and partner-to-ZNF552 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX47 grouped by ZNF552-low versus ZNF552-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF552→partner) and Y-score (partner→ZNF552) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	TEX47 →	+0.310	+5.357	<.001	.001	3	1
CNS	S100G →	+0.132	+4.321	<.001	.009	3	1
LARGE_INTESTINE	ELOA3DP →	+0.044	+4.273	<.001	.006	3	1
STOMACH	MBD3L2B →	+0.042	+4.432	<.001	.003	3	1
STOMACH	TRIM49D2 →	+0.030	+4.285	<.001	.007	3	1
STOMACH	SCYGR2 →	+0.087	+4.285	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

TEX47 by ZNF552 expression — CNS

Explore this box plot interactively →