ZNF550

Across TCGA patient cohorts, ZNF550 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,625 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF550-associated proteins across cancer lineages are XRCC1, TRIM28, and PNKP. Each is linked with ZNF550 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF550-to-partner and partner-to-ZNF550 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF550 versus XRCC1 in LSCC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF550→partner) and Y-score (partner→ZNF550) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	XRCC1 →	+0.324	+0.419	.001	.001	3	6
GBM	TRIM28 →	+0.482	+0.612	<.001	<.001	3	5
HNSC	PNKP →	+0.330	+0.736	<.001	<.001	3	5
GBM	RBM12 →	+0.281	+0.382	<.001	<.001	3	5
LSCC	WDR70 →	+0.350	+0.333	.002	.003	3	5
COAD	ZMYM3 →	+0.477	+0.646	.003	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,625 associations by consensus.

ZNF550 vs XRCC1 — LSCC

Explore this scatter interactively →