ZNF518A

Across TCGA patient cohorts, ZNF518A protein abundance is significantly associated with the RNA expression of many other genes, with 461 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZNF518A-associated genes across cancer lineages are TSPAN5, TSNAXIP1, and NUCB1. Each is linked with ZNF518A in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF518A-to-partner and partner-to-ZNF518A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF518A versus TSPAN5 in BRCA, with a Pearson correlation of -0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF518A→partner) and Y-score (partner→ZNF518A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TSPAN5 →	-1.466	-0.583	.005	.002	3	2
LSCC	TSNAXIP1 →	+0.350	+0.302	.008	.003	3	1
LSCC	NUCB1 →	-0.428	-0.417	.003	.001	3	1
LSCC	FAAP24 →	+0.534	+0.310	.002	.002	3	1
LSCC	CLSTN3 →	-0.663	-0.362	<.001	.003	3	1
LSCC	INPP1 →	-0.851	-0.347	.004	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 461 associations by consensus.

ZNF518A vs TSPAN5 — BRCA

Explore this scatter interactively →