ZNF518A

Across TCGA patient cohorts, ZNF518A protein abundance is significantly associated with the protein abundance of many other proteins, with 1,772 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF518A-associated proteins across cancer lineages are ZNF638, RFX3_S674, and RGS12_S107. Each is linked with ZNF518A in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF518A-to-partner and partner-to-ZNF518A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF518A versus ZNF638 in UCEC, with a Pearson correlation of -0.40.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF518A→partner) and Y-score (partner→ZNF518A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZNF638 →	-0.243	-0.361	<.001	<.001	3	1
LSCC	RFX3_S674 →	+0.768	+0.496	<.001	<.001	3	1
LSCC	RGS12_S107 →	+1.014	+0.786	.001	.003	3	1
LSCC	SGSH →	-0.248	-0.336	<.001	<.001	3	1
LSCC	SH3BP4_S122 →	+0.920	+0.698	<.001	.002	3	1
LSCC	SHANK3_T349 →	-1.066	-0.525	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,772 associations by consensus.

ZNF518A vs ZNF638 — UCEC

Explore this scatter interactively →