ZNF518A

Across TCGA patient cohorts, ZNF518A mutation is significantly associated with the RNA expression of many other genes, with 6,201 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF518A-associated genes across cancer lineages are RNA5SP415, HMGB1P24, and RNU7-37P. Each is linked with ZNF518A in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF518A-to-partner and partner-to-ZNF518A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP415 grouped by ZNF518A-low versus ZNF518A-high in ESCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF518A→partner) and Y-score (partner→ZNF518A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	RNA5SP415 →	+0.503	+7.303	<.001	<.001	3	4
UCEC	HMGB1P24 →	+0.191	+1.912	.001	<.001	3	3
ESCA	RNU7-37P →	+1.464	+5.247	<.001	.006	3	3
READ	MIR4774 →	+0.627	+5.257	<.001	.002	3	3
CESC	RNA5SP308 →	+1.199	+6.164	<.001	<.001	3	3
COAD	VAPA →	+0.421	+2.713	.005	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,201 associations by consensus.

RNA5SP415 by ZNF518A expression — ESCA

Explore this box plot interactively →